Basavaraj Teli, Jyotika Purohit, Md. Mahtab Rashid, A. Abdul Kader Jailani and Anirudha Chattopadhyay* Pages 1 - 18 ( 18 )
In the scenario of global warming and climate change, an outbreak of new pests and pathogens has become a serious concern owing to the rapid emergence of arms races, their epidemic infection, and the ability to break down host resistance, etc. Fusarium head blight (FHB) is one such evidence that depredates major cereals throughout the world. The symptomatological perplexity and aetiological complexity make this disease very severe, engendering significant losses in the yield. Apart from qualitative and quantitative losses, mycotoxin production solemnly deteriorates the grain quality in addition to life endangerment of humans and animals after consumption of toxified grains above the permissible limit. To minimize this risk, we must be very strategic in designing sustainable management practices constituting cultural, biological, chemical, and host resistance approaches. Even though genetic resistance isthe most effective and environmentally friendly strategy, a huge genetic variation and unstable resistance response limit the holistic deployment of resistance genes in FHB management. Thus, the focus must shift towardsthe editing of susceptible (S) host proteins that are soft targets of newly evolving effector molecules, which ultimately could be exploited to repress the disease development process. Hence, we must understand the pathological, biochemical, and molecular insight of disease development in a nutshell.In the present time,the availability of functional genomics, proteomics, and metabolomics information on host-pathogen interaction in FHB have constructed various networks whichhelped in understanding the events of pathogenesis and coherent host response(s). So now translation of this information for designing of host defense in the form of desirable resistant variety/genotype is the next step. The insightscollected and presented in this review will be aiding understanding the disease and apprise a solution to the multi-faceted problems which are related to FHB resistance in wheat and other cereals to ensure global food safety and food security.
FHB, FGSC, mycotoxin, host defense, wheat, RNA interference, genome editing
Department of Mycology and Plant Pathology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi, Department of Plant Pathology, C.P. College of Agriculture, S.D. Agricultural University, S. K. Nagar, Department of Mycology and Plant Pathology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi, Plant RNAi Biology Group, I.C.G.E.B., New Delhi, Department of Plant Pathology, C.P. College of Agriculture, S.D. Agricultural University, S. K. Nagar