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Single-cell RNA Sequencing in Immunology

[ Vol. 21 , Issue. 8 ]

Author(s):

Yirui Cao, Yue Qiu, Guowei Tu* and Cheng Yang*   Pages 564 - 575 ( 12 )

Abstract:


The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions.

Keywords:

Single-cell RNA sequencing, immunology, cancer, autoimmune disease, transplantation, tumors.

Affiliation:

Department of Urology, Zhongshan Hospital, Fudan University; Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, Department of Urology, Zhongshan Hospital, Fudan University; Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032

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